Robert Mitchell has a great piece, Skype Slips into Business, that looks in some detail about how Skype is being used in a variety of business environments.

I resisted Skype for a long time, but now find it invaluable. I'm also recommending it to associates, especially those smaller companies that have multiple sites, but don't (understandably) want to spend hundreds, or even thousands, of pounds communicating between sites.

In the article, the usage of Skype by support and their employment of SkypeOut as part of a solution for providing unified access to a group resource, is interesting. The article also highlights some of the limitations of the Skype environment.