As outline in this announcement from Skype yesterday, Skype making its way into businesses, Skype is gaining a lot of momentum for communicating between businesses and offices as a cheap and viable alternative to using the standard phone system. For those companies that spend a lot of time talking between different branches the potential savings could be huge just on the inter-branch calls.
Certainly the new business focus will be a step in the right direction for those companies not only using Skype for basic calls, but also for those companies that want to extend their Skype usage elsewhere.