I've been using an Intel based Mac as my main machine now for a few months, first with the developer transition kit (DTK), and now with the shiny iMac Core Duo that Apple sent as replacement for that unit. However, I can see it taking a long time before I reach even an all-Intel version of old environment, and for some applications I may never get an Intel version.
The problem with any transition like this (and remember that any long time Mac user like myself will remember the move from 68k to PowerPC) is waiting for the applications that you use regularly to be migrated to the new platform.